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Automated pharmacovigilance literature validation for ultra‑rare neurological diseases. Enter a drug name and an adverse event. The app searches PubMed with a multi‑tier cascade, extracts the most relevant evidence, and returns a verdict — Present or Absent — backed by a fine‑tuned PubMedBERT model.
Transformer-based topic modeling (BERTopic) of six spine journals, 1978–2026 — 40,401 abstracts, 37 topics, with temporal trends and VOSviewer comparison.
Local multi-agent pipeline (LLaMa-3.1 via MLX + PubMedBERT RAG over Chroma) that fact-checks drug questions against authoritative medical sources and returns a cited answer with per-claim verdicts. Ships with a FastAPI + single-page web UI and a Typer CLI
Fine-tuned PubMedBERT bi-encoder on PubMedQA achieving NDCG@10=0.974. BM25 from scratch in pure NumPy. Self-improving multi-agent critic loop. Model live on HuggingFace Hub.
Biotech venture valuation workbench: reflexivity-adjusted PoS, phase-stratified ML prior trained on real HINT outcomes (externally validated against CT Open uncontaminated), phase-gated rNPV with Monte Carlo, 8-pillar diligence scorecard, cited deal comparables. Modular registry architecture with three runtime agents.