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@lacdr-tox

LACDR-CDS - Beltman lab

Assoc. Prof. Dr. Joost Beltman is head of the Image-based Computational Biology group at the LACDR Division of Cell Systems and Drug Safety (CDS)

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  1. basic-programming-in-drug-discovery basic-programming-in-drug-discovery Public

    Course materials for basic programming in drug discovery

    Jupyter Notebook 4 3

  2. cellprofiler-plugins cellprofiler-plugins Public

    1

  3. Leegwater_lipidomics_normalization Leegwater_lipidomics_normalization Public

    Code to generate figures for "Normalization strategies for lipidome data in cell line panels" (Leegwater et al. 2024)

    R 1

  4. ClonalGrowthSimulator_SSA ClonalGrowthSimulator_SSA Public

    Gillespie simulator of clonal growth

    C++ 1

  5. ClonalGrowthSimulator_ABM ClonalGrowthSimulator_ABM Public

    Agent based simulator of clonal growth

    C++

  6. wmc_imagej wmc_imagej Public

    Macro to use WMC segment in batch mode in Fiji

Repositories

Showing 10 of 29 repositories
  • DiTillio_Gentamicin-nephrotox Public

    Material for "A Transcriptomics-Driven Quantitative Adverse Outcome Pathway Network Model for Gentamicin-Induced Nephrotoxicity"

    lacdr-tox/DiTillio_Gentamicin-nephrotox's past year of commit activity
    R 0 1 0 0 Updated Jun 11, 2026
  • Burgers_PBPKAdversity Public

    Repository containing data and code corresponding to the manuscript "Towards a novel toxicity prediction pipeline, combining PBPK models and mechanistic cellular adversity models" by Burgers et al.

    lacdr-tox/Burgers_PBPKAdversity's past year of commit activity
    Python 0 MIT 0 0 0 Updated May 8, 2026
  • Burgers_OSRISR Public

    Repository corresponding to the article: Mathematical modelling reveals compound-specific stress pathway activity by Burgers et al. Toxicology (2025)

    lacdr-tox/Burgers_OSRISR's past year of commit activity
    HTML 0 MIT 0 0 0 Updated Mar 17, 2026
  • Sharma_NRF2_SRXN1_Semimechanistic_modeling Public
    lacdr-tox/Sharma_NRF2_SRXN1_Semimechanistic_modeling's past year of commit activity
    R 0 MIT 0 0 0 Updated Sep 23, 2025
  • Leegwater_lipidomics_normalization Public

    Code to generate figures for "Normalization strategies for lipidome data in cell line panels" (Leegwater et al. 2024)

    lacdr-tox/Leegwater_lipidomics_normalization's past year of commit activity
    R 1 MIT 0 0 0 Updated Aug 6, 2025
  • Winkelman_ABLbinding Public

    Repository for article: 'Pyroglutamation of cell surface proteins CD47 and TRP1 by glutaminyl cyclase modulates therapeutic antibody binding', van der Plas - van Duijn et al., Communications Biology, 2025

    lacdr-tox/Winkelman_ABLbinding's past year of commit activity
    R 0 MIT 0 0 0 Updated Jul 24, 2025
  • Burgers_DDROSR Public
    lacdr-tox/Burgers_DDROSR's past year of commit activity
    Python 0 MIT 0 0 0 Updated Feb 10, 2025
  • heldring-E2S-modeling Public

    Data and code used for the manuscript titled "Interdependency of estradiol-mediated ERα activation and subsequent PR and GREB1 induction to control cell cycle progression"

    lacdr-tox/heldring-E2S-modeling's past year of commit activity
    Jupyter Notebook 0 MIT 0 0 0 Updated Sep 14, 2024
  • FunGen2024 Public

    Code to test if DESeq2 can be run for the bachelor course Functional Genomics

    lacdr-tox/FunGen2024's past year of commit activity
    0 0 0 0 Updated Jun 21, 2024
  • Sharma_Nitrofurantoin_PBPKmodeling Public
    lacdr-tox/Sharma_Nitrofurantoin_PBPKmodeling's past year of commit activity
    R 0 MIT 0 0 0 Updated Aug 23, 2023
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