This repository hosts a master’s student project on improving bulk ATAC-seq data analysis at the DRESDEN-concept Genome Center. The project will review available tools and workflows, assess the current in-house analysis approach based on nf-core, and identify opportunities for improvement. A particular focus will be placed on suitable peak calling, and the implementation of differential accessibility analysis. The aim is to develop a well-documented and reproducible workflow that can serve as a practical basis for future DcGC projects.