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docs: synthesis pool now 7 scaffold families after PR #72 (SEED-001 re-entered) - #76
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…#72) PR #72 face_segregation_bonus improved magainin-1 (SEED-001) competitive ranking: - Synthesis pool: 6→7 scaffold families; SEED-001 contributes 5 candidates - SEED-002 remains excluded; all other counts updated - Candidate family priority table updated with current pool counts - Pilot panel serum stability section updated with correct family count All 20 pilot panel candidates still pass disagreement gate (max dis=0.4449 < 0.45)
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Summary
The PR #72 face_segregation_bonus improved the competitive ranking of SEED-001 (magainin-1, Xenopus laevis) variants, bringing them back into the synthesis pool for the first time.
Before PR #72: 6 scaffold families — SEED-003 (16), SEED-005 (4), SEED-006 (10), SEED-007 (27), SEED-008 (24), SEED-009 (19)
After PR #72: 7 scaffold families — SEED-001 (5), SEED-003 (14), SEED-005 (3), SEED-006 (10), SEED-007 (26), SEED-008 (24), SEED-009 (18)
This is a positive development — magainin is one of the best-studied AMP scaffolds in the literature.
Changes:
DISCOVERY_PREDICTION.md: updated "6 scaffold families" → "7 scaffold families" in 4 locations, updated candidate counts, added SEED-001 entry to priority tableSafety check:
All 20 pilot panel candidates still pass the disagreement gate (max dis=0.4449 < 0.45 threshold).
Test plan
make pilotoutput shows 7 seeds, counts match updated docs🤖 Generated with Claude Code